University of California San Francisco

Conte Lab - Homepage

Dr. Michael Conte

Michael S. Conte, MD

  • Interim Chief, Division of Cardiothoracic Surgery
  • Professor and Chief, Division of Vascular & Endovascular Surgery
  • Edwin J. Wylie, M.D. Chair in Vascular Surgery
  • Co-Director, UCSF Heart and Vascular Center
  • Co-Director, UCSF Center for Limb Preservation
  • Director, Vascular Surgery Integrated Residency Program
  • Director, Vascular Surgery Fellowship Program

Mechanisms of Vascular Injury and Remodeling

The Conte Lab conducts basic laboratory investigations that are focused on understanding and improving the healing response of blood vessels following angioplasty and bypass surgery, with the goal of improving the long-term results of these common operations. Specifically, the laboratory investigates the vascular biology of restenosis and the vessel wall response to injury. We are interested in the molecular pathways which govern the survival and growth of endothelial and smooth muscle cells at site of blood vessel injury. We have also had a long-standing interest in the local delivery of genes, small molecules and drugs to blood vessels. His research is funded by the National Institutes of Health and other extramural sources.

Our Research

Dr. Conte's research is focused on developing new molecular therapies to improve the long-term results of cardiovascular procedures. His translational research program includes basic laboratory investigations as well as prospective clinical trials to study the causes of failure of angioplasty and bypass surgery and develop new approaches to stratify patients at risk.

Research Pathways

Grants and Funding

  • UCSF Diabetic Foot Clinical Research Unit | NIH | 2018-09-15 - 2022-06-30 | Role: Principal Investigator
  • Tissue Oxygen Monitoring in Peripheral Vascular Disease | NIH | 2016-04-01 - 2021-07-31 | Role: Co-Principal Investigator
  • Specialized lipid mediators and mechanisms of resolution in vascular injury | NIH | 2013-08-21 - 2018-05-31 | Role: Principal Investigator
  • IGF::OT::IGF VASCULAR INTERVENTIONS/INNOVATIONS AND THERAPEUTIC ADVANCES (VITA): PRO-RESOLVING VASCULAR DEVICES BASE PERIOD: NOVEMBER 15, 2013 - NOVEMBER 14, 2014 | NIH | 2013-11-15 - 2014-11-14 | Role: Principal Investigator
  • Survivin: a novel regulator of intimal hyperplasia and vein graft remodeling | NIH | 2007-08-01 - 2013-06-30 | Role: Principal Investigator
  • General Clinical Research Center | NIH | 1984-12-01 - 2010-03-31 | Role: Co-Investigator
  • GENETIC ENGINEERING OF A FAILURE RESISTANT VEIN GRAFT | NIH | 1999-09-07 - 2004-08-31 | Role: Principal Investigator

Twitter

Featured News

Featured Publications

  1. Better limb staging in chronic limb-threatening ischemia: Why it matters.
    2024 | PubMed
  2. A Novel Preoperative Risk Score to Identify Patients at High Risk for Non-Home Discharge After Elective Open Abdominal Aortic Aneurysm Repair.
    2024 | PubMed
  3. The Impact of Diabetes Mellitus on the Outcomes of Revascularization for Chronic Limb-Threatening Ischemia in the BEST-CLI trial.
    2024 | PubMed
  4. Prosthetic Conduits have Worse Outcomes compared to Great Saphenous Vein Conduits in Femoropopliteal and Infrapopliteal Bypass in Patients with Chronic Limb Threatening Ischemia.
    2024 | PubMed
  5. Antithrombotic Strategies for Patients With Peripheral Artery Disease: JACC Scientific Statement.
    2024 | PubMed
Support our Research
Conte and Vascular Lab photo

A gift to the Conte Lab helps support research to treat serious conditions such as PAD, aneurysms, and carotid artery disease. 

Make a Gift