University of California San Francisco

Conte Lab - Homepage

Dr. Michael Conte

Michael S. Conte, MD

  • Interim Chief, Division of Cardiothoracic Surgery
  • Professor and Chief, Division of Vascular & Endovascular Surgery
  • Edwin J. Wylie, M.D. Chair in Vascular Surgery
  • Co-Director, UCSF Heart and Vascular Center
  • Co-Director, UCSF Center for Limb Preservation
  • Director, Vascular Surgery Integrated Residency Program
  • Director, Vascular Surgery Fellowship Program

Mechanisms of Vascular Injury and Remodeling

The Conte Lab conducts basic laboratory investigations that are focused on understanding and improving the healing response of blood vessels following angioplasty and bypass surgery, with the goal of improving the long-term results of these common operations. Specifically, the laboratory investigates the vascular biology of restenosis and the vessel wall response to injury. We are interested in the molecular pathways which govern the survival and growth of endothelial and smooth muscle cells at site of blood vessel injury. We have also had a long-standing interest in the local delivery of genes, small molecules and drugs to blood vessels. His research is funded by the National Institutes of Health and other extramural sources.

Our Research

Dr. Conte's research is focused on developing new molecular therapies to improve the long-term results of cardiovascular procedures. His translational research program includes basic laboratory investigations as well as prospective clinical trials to study the causes of failure of angioplasty and bypass surgery and develop new approaches to stratify patients at risk.

Research Pathways

Grants and Funding

  • UCSF Diabetic Foot Clinical Research Unit | NIH | 2018-09-15 - 2022-06-30 | Role: Principal Investigator
  • Tissue Oxygen Monitoring in Peripheral Vascular Disease | NIH | 2016-04-01 - 2021-07-31 | Role: Co-Principal Investigator
  • Specialized lipid mediators and mechanisms of resolution in vascular injury | NIH | 2013-08-21 - 2018-05-31 | Role: Principal Investigator
  • IGF::OT::IGF VASCULAR INTERVENTIONS/INNOVATIONS AND THERAPEUTIC ADVANCES (VITA): PRO-RESOLVING VASCULAR DEVICES BASE PERIOD: NOVEMBER 15, 2013 - NOVEMBER 14, 2014 | NIH | 2013-11-15 - 2014-11-14 | Role: Principal Investigator
  • Survivin: a novel regulator of intimal hyperplasia and vein graft remodeling | NIH | 2007-08-01 - 2013-06-30 | Role: Principal Investigator
  • General Clinical Research Center | NIH | 1984-12-01 - 2010-03-31 | Role: Co-Investigator
  • GENETIC ENGINEERING OF A FAILURE RESISTANT VEIN GRAFT | NIH | 1999-09-07 - 2004-08-31 | Role: Principal Investigator

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Featured News

Featured Publications

  1. Outcomes of chronic limb-threatening ischemia revascularization in patients with chronic kidney disease in the BEST-CLI trial.
    2025 | PubMed
  2. Vascular Quality Initiative Assessment of Compliance with Society for Vascular Surgery Practice Guidelines for the Endovascular Management of Claudication.
    2025 | PubMed
  3. Low rates of aortic surveillance imaging and clinical follow-up in patients with acute aortic dissection.
    2024 | PubMed
  4. Large language models can accurately populate Vascular Quality Initiative procedural databases using narrative operative reports.
    2024 | PubMed
  5. Advanced WIfI Stage is Associated with Poor Outcomes in the BEST-CLI Trial.
    2024 | PubMed
Support our Research
Conte and Vascular Lab photo

A gift to the Conte Lab helps support research to treat serious conditions such as PAD, aneurysms, and carotid artery disease. 

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